The USBJI thanks Faculty for their commitment and dedication to the YII program and the time they invest in mentoring the upcoming generation of MSK investigators.
Nancy Lane, MD (Chair)
Nancy Baker, ScD, MPH, OTR/L
Lauren Beaupre, PT, PhD
Mary Bell, MD, MSc
Leigh Callahan, PhD
Yasin Y. Dhaher, PhD
Henry Donahue, PhD
Hicham Drissi, PhD
Dorothy Dunlop, PhD
Kristine Ensrud, MD, MPH, MACP
Yvonne Golightly, PT, MS, PhD
Stuart Goodman, MD, PhD, FRCSC, FACS, FBSE, FICORS
Edward Greenfield, PhD
Marian Hannan, DSc, MPH
Howard Hillstrom, PhD
Christopher Jacobs, PhD - In memoriam
Joshua J. Jacobs, MD
Susan Jaglal, PhD
Wendy Katzman, PT, DPTSc, DSc
Anne-Marie Malfait, MD, PhD
Braxton Mitchell Jr., MPH, PhD
Fackson Mwale, PhD
Brian Norhren, PT, PhD
Jacques E. Nör, DDS, MS, PhD
Regis H. O'Keefe, MD, PhD
Edward Puzas, PhD
Stephen Robinovitch, PhD
Ann Rosenthal, MD
Alice Ryan, PhD
Stephen Waldman, PhD
Cari Whyne, PhD
Albert Yee, MD, MSc, FRCSC
Lidan You, PhD, P.Eng., FCSME
Yuqing Zhang, DSc
|Nancy Baker, ScD, MPH, OTR/L
Dr. Baker, ScD, MPH, OTR/L, is chair of the Experts in Arthritis Advisory Committee. She is responsible for the team which develops, reviews and maintain the evidence-based content. The team also provides direction of the program, monitors and oversees its progress and performance. Dr. Baker is an Associate Professor in the Department of Occupational Therapy at Tufts University. She received her BS in occupational therapy from Tufts University in 1985. She was a clinical occupational therapist for 11 years, specializing in industrial rehabilitation and ergonomics. In 2000 she received a doctorate in Therapeutic Studies from Sargent College, Boston University and in 2009 she received a Master of Public Health in Epidemiology from the Graduate School of Public Health at the University of Pittsburgh, where she was an Associate Professor until 2018. Dr. Baker’s research focuses on the prevention and treatment of musculoskeletal disorders, particularly those related to job performance. She has obtained foundation and federal funding to study computer ergonomics and innovative treatments for carpal tunnel syndrome. From 2014 to 2015 she spent a sabbatical year as a Visiting Researcher at the CDC’s Arthritis Program.
|Lauren Beaupre, PT, PhD
Dr. Beaupre is a professor at the University of Alberta, Canada. She holds a joint appointment in Physical Therapy and the Division of Orthopaedic Surgery. Her research program focuses on clinical outcome and health services research in patients who sustain musculoskeletal injuries. She is the National Hip Fracture Director for Bone and Joint Canada.
|Mary J. Bell, MD, MSc, FRCPC
Dr. Bell received her BSc in Physical Therapy from McGill University in 1973 and her MD from McMaster University in 1979. She completed Royal College of Canada Postgraduate Training in Internal Medicine and Rheumatology at the University of Toronto in 1988. She obtained a Master of Science from the Department of Clinical Epidemiology and Biostatistics, McMaster University in 1988.
Dr. Bell joined the Department of Medicine at the University of Toronto in 1991 as a Clinical Investigator located at the Sunnybrook Health Sciences Centre. From 2002 to 2009, she served as Head of the Sunnybrook Division of Rheumatology. She was Director, Continuing Education and Knowledge Translation & Exchange in the Department of Medicine at the University of Toronto July 2006-June 2011. Her mandate in this role is to increase the capacity of faculty to deliver continuing education, foster knowledge translation, increase skill in output in the area of continuing education research, and better integrate faculty with practicing clinicians in the community through collaborative educational activities. Dr. Bell is an Associate Professor of Medicine.
Dr. Bell was the lead investigator on the National Getting a Grip on Arthritis Project, funded by Health Canada’s Primary Health Care Transition Fund. She has received extensive accolades for her contributions to this effort culminating in the Dave Davis Continuing Education & Professional Development Research Award in 2007.
Dr. Bell’s outstanding contribution as the National Director of the Patient Partners® in Arthritis Program was formally recognized in 2001 with the W.T. Aikins Faculty Teaching Award for the development and national implementation of this program; a program whereby people with arthritis are trained in musculoskeletal anatomy, communication skills and in the conduct of the musculoskeletal physical examination. They then teach these skills to trainees and practicing clinicians alike. Under her leadership from 1995-2007, this program grew in international reputation.
Dr. Bell is involved in several other research projects in the areas of patient education, medical education, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and osteoporosis. Throughout her career at the University of Toronto she has been a Research Scientist at the Arthritis Community Research and Evaluation Unit (ACREU) located in the Arthritis and Immune Disorder Research Centre at the University Health Network in Toronto and the Sunnybrook Research Institute.
|Leigh F. Callahan, PhD
Dr. Leigh F. Callahan is the Mary Link Briggs Distinguished Professor of Medicine in the School of Medicine, and Professor in the Departments of Social Medicine and Orthopaedics at the University of North Carolina, Chapel Hill, NC. She is the Associate Director of the Thurston Arthritis Research Center which is part of the School of Medicine at the University of North Carolina at Chapel Hill. In addition, she is Director of Community and Outcomes Research in the Thurston Arthritis Research Center and directs the Osteoarthritis Action Alliance. Dr. Callahan has over 30 years of experience in arthritis and health outcomes research. She is a former arthritis epidemiologist with the Centers for Disease Control and Prevention.
Dr. Callahan has served on a number of editorial boards, is a former editor for the Arthritis Care and Research journal and has been a reviewer for numerous journals including the Journal of Rheumatology, Arthritis and Rheumatism, JAMA, Annals of Internal Medicine, and Medical Care. She served on the Institute of Medicine (IOM) committee that produced the 2012 report, Living well with chronic illness: A call for public health action. She has served on numerous committees for the US Decade of Bone and Joint Disease as well as the of Board of Directors Dr. Callahan is a long-time volunteer for the Arthritis Foundation (AF) on both the state and national level, and received the Charles B. Harding Award for Distinguished Service in 2005 for her work with the Foundation. In 2006, she received the Addie Thomas Service Award from the Association of Rheumatology Health Professionals. She has authored more than 200 publications and articles, is a frequent presenter at conferences and meetings worldwide, and continues to spearhead a number of projects examining the factors surrounding arthritis, health outcomes, and health disparities. She has received numerous grants from the NIH and CDC.
|Yasin Y. Dhaher, PhD
Dr. Dhaher is the R. Wofford Cain Distinguished Chair in Bone and Joint Disease Research, Vice Chair of Research, Department of Physical Medicine, Vice Chair of Research, Department of Orthopaedic Surgery, Professor of Physical Medicine and Rehabilitation, Orthopaedic Surgery, and Bioengineering, and the Director of the Mobility Foundation Center Fund at the UT Southwestern. The central theme of his research is to understand the basic neurophysiological properties of the lower limb after a neurological lesion. The primary goal of these investigations is to evaluate and improve rehabilitation interventions after neurological disabilities. His research program has investigated various pathologies such as stroke, spinal cord injury and visual vertigo. In addition to focusing on the basic science related to these pathologies, his research has also often expanded to include treatment interventions (robotic rehabilitations, etc...) for these diseases. He has published more than 120 papers in peer reviewed journals and conference proceedings and given more than 30 invited talks.
Dr. Dhaher served on a number of grant review panels, including the MRS study section, National Institutes of Health (a standing member); MSM review panel, NIBIB-NIH special initiative (ad Hoc); Special Emphasis Panel, NIAMS-NIH (ad Hoc); the Defense Advanced Research Projects Agency, DARPA (ad Hoc); and the Thiel Foundation. He served as the Associate Editor for the IEEE Transactions on Biomedical Engineering and an Associate Editor/Editor (serving) for the Annual International Conference of the IEEE Engineering in Medicine and Biology Society and serves on the International Conference of Rehabilitation Robotics steering committee. He has served on the program committees of many national and international scientific meetings.
|Henry J. Donahue, PhD
Dr. Donahue is the Michael and Myrtle Baker Professor, Vice Chair for Research and Director, Division of Musculoskeletal Sciences in the Department of Orthopaedics and Rehabilitation at Pennsylvania State University College of Medicine. His work focuses on bone cell and molecular biology especially as it relates to bone adaptation to mechanical load, osteoporosis and skeletal regeneration and tissue engineering.
Dr. Donahue has been continually funded as a Principal Investigator by NIH for over 25 years and has also had funding from the Department of Defense, NASA, private foundations and industry. He is currently funded by NIH, the Department of Defense, the Musculoskeletal Tissue Foundation and NASA.
Dr. Donahue has served on numerous NIH study sections as well as review panels in Canada and Europe.
|Hicham Drissi, PhD
Dr. Drissi is currently a tenured Professor of Orthopaedic Surgery and the Vice Chair of Orthopaedic Research at Emory University. Dr. Drissi is also a Professor of Cell Biology at Emory University. In addition to his ongoing research program, he oversees the orthopaedic research programs at Emory University. Prior to his current position, Dr. Drissi served as a tenured Professor of Orthopaedic Surgery and the Director of Orthopaedic Research within the New England Musculoskeletal Institute at the University of Connecticut Health Center. He was also a Professor of Genetics and Genome Sciences at the University of Connecticut Health Center. Dr. Drissi obtained his Ph.D. from Université René Descartes. Université Paris V, Paris, France in Cell and Molecular Biology. He began his independent investigator career in 2002 as an Assistant Professor in the Department of Orthopaedic Surgery at the University of Rochester upon completion of his post-doctoral training and initial faculty position at the University of Massachusetts Medical School.
Throughout his career, Dr. Drissi received multiple grants as PI, co-PI or co-I form NIH, DOD, State funding agencies as well as from the pharmaceutical industry and philanthropic donors. Dr. Drissi’s research focuses on understanding the molecular pathways that govern skeletal development, repair and regeneration. His contributions to the field of musculoskeletal research relate to understanding the mechanisms underlying the control of osteoblast, chondrocyte and osteoclast differentiation in vitro and in vivo. He also developed a funded program in stem cell use for cartilage and intervertebral disc tissue repair and regeneration and is currently the scientific program director of a multicenter clinical trial for stem cell treatment of knee osteoarthritis. Dr. Drissi has published over 100 peer-reviewed manuscripts and served on the editorial board of JBMR and currently serves as an editorial board member of J Cell Biochem and as an Associate Editor of Techniques in Orthopaedics and Genes and Genomes. He is also a handeling Editor for Bone. He has mentored multiple postdoctoral fellows most of which have secured faculty positions. He also mentored several orthopaedic residents for their research projects, most of which have graduated and secured academic positions with strong research interests. Dr. Drissi’s research is also geared towards identifying better treatment strategies for US Veterans and the majority of his research effort takes place at the Atlanta VA.
Dr. Drissi served as ad-hoc reviewer on grant review panels from the National Institute of Health (NIH), The Department of Defense (DOD), the Veterans Affairs (VA), the National Science Foundation (NSF), the Israel Science Foundation, the United States-Israel Binational Science Foundation, the Australian National Health and Medical Research Council (ANHMRC), the Arthritis Foundation, the NYSTEM Musculoskeletal Peer Review Panel as well as other national and international granting agencies.
Dr. Drissi is an avid advocate for junior investigators. He has served as a faculty mentor and moderator in several ORS/OREF/AAOS joint New Investigator Workshops. He has and continues to serve as mentor to several basic and clinician scientists. The junior faculty he mentored within his past institutions obtained their first grant from foundations, state or federal agencies. Particularly, Dr. Drissi has extensive experience working with orthopedic surgeons who aim to develop an academic career as physician scholars.
|Dorothy Dunlop, PhD
Dr. Dunlop is a Professor of Medicine and Preventive Medicine at Northwestern University Feinberg School of Medicine, Institute for Public Health and Center for Healthcare Studies
She is a health services researcher with expertise in statistical methodology. Her applied research interests include the investigation of physical activity to prevent disability in older adults. Her research activities include the investigation of risk factors in arthritis populations for disability, high medical costs, and utilization of health services. She is principal investigator on studies funded through the National Institutes for Health (NIH).
Dr. Dunlop has served on advisory boards for national clinical trials funded through the NIH, the Agency for Healthcare Research and Quality (AHRQ), and the Department of Veterans affairs. Her study section service as a peer reviewer includes the NIH (NAME, AMS), ACR Research Education Foundation, the Arthritis Foundation, and the Department of Veterans Affairs.
|Kristine E. Ensrud, MD, MPH, MACP
Kristine Ensrud, MD, MPH, MACP is a Professor of Medicine and Epidemiology & Community Health at the University of Minnesota and Core investigator and Staff Physician at the Minneapolis VA Health Care System. Her expertise is the epidemiology and treatment of age-related conditions including osteoporosis and related-fractures; menopausal symptoms; sleep disorders; chronic kidney disease; impairments in mobility and cognition; functional limitations; and frailty.
Dr. Ensrud has authored over 450 publications including several articles in the New England Journal of Medicine, Journal of the American Medical Association, Annals of Internal Medicine, and British Medical Journal. She has had continuous NIH funding for over 25 years serving as Principal Investigator of long term NIH-funded prospective cohort studies in older adults and played a leading role in the design, conduct, and analysis of these studies. More recently, Dr. Ensrud has merged these comprehensive cohort datasets with Medicare claims data to identify unique determinants of health care utilization and costs in aged populations. Her work has also been instrumental in the design, conduct and analysis of large, multi-center randomized clinical trials evaluating the efficacy and safety of pharmacologic treatments for osteoporosis, menopausal symptoms and age-related hypogonadism in older men.
Dr. Ensrud is a general internist and has an active primary care practice focused on women veterans and provides inpatient and outpatient teaching to medical students and residents. She served as the Director of the University of Minnesota Epidemiology Clinical Research center from 2002-2015, has served on numerous national scientific review panels and steering committees, and actively mentors the next generation of clinical researchers including fellows and junior investigators. Dr. Ensrud has received numerous honors and awards, including the Outstanding Faculty Mentor Award and Wall of Scholarship awards from the University of Minnesota Medical School in 2014 as well as election to the Association of American Physicians and Mastership in the American College of Physicians in 2017.
|Yvonne Golightly, PT, MS, PhD
Dr. Golightly is an assistant professor at the University of North Carolina at Chapel Hill in the Department of Epidemiology with an adjunct appointment in the Division of Physical Therapy. She is a musculoskeletal epidemiologist and a physical therapist with over a decade of research and clinical experience. Her research interests include osteoarthritis, musculoskeletal injury, lower body musculoskeletal disorders, biomechanics, and physical activity. She has worked with the Johnston County Osteoarthritis Project for over 12 years and has authored or co-authored over 20 publications using data from this cohort. In 2017, she became co-Principal Investigator of this project. She is the Principal Investigator of an R01 project “The Role of Joint Hypermobility in Lower Body Osteoarthritis,” and an R21 titled “High Intensity Interval Training for Knee Osteoarthritis.”
|Stuart B. Goodman MD MSc PhD FRCSC FACS FBSE FICORS
Stuart B. Goodman is the Robert L. and Mary Ellenburg Professor of Surgery, and Professor with Tenure in the Department of Orthopaedic Surgery at Stanford University. He has a courtesy appointment in the Department of Bioengineering, and is a Fellow of the Institute of Chemistry, Engineering and Medicine for Human Health (ChEM-H) at Stanford University. He was Chief of Orthopaedic Surgery at Stanford University from 1994-2002. Dr. Goodman received his BSc, MD and MSc (Institute of Medical Science) from the University of Toronto, and his PhD in Orthopedic Medical Science from Lund University in Sweden. He is a Fellow of the Royal College of Surgeons (Canada), the American Academy of Orthopaedic Surgeons and the American College of Surgeons. Dr. Goodman's clinical practice concentrates on adult reconstructive surgery. His clinical research interests center on the outcome of surgery for arthritis including primary and revision total joint replacement, juvenile arthritis, and osteonecrosis of the hip and knee. His basic science interests center on biocompatibility of orthopaedic implants, inflammation, and musculoskeletal tissue regeneration and repair. Dr. Goodman is a member of numerous academic organizations including former Chairman of the AAOS Biological Implants Committee, and a former member of the AAOS Biomedical Engineering Committee. He is a member of the Hip Society, Knee Society and AAHKS, a consultant to the Orthopaedic and Rehabilitation Devices Advisory Panel of the FDA, and former vice-chairman of the Musculoskeletal Tissue Engineering study section at NIH. Dr. Goodman is on the editorial board of the Journal of Orthopaedic Research (Associate Editor), Clinical Orthopaedics (Deputy Editor-Hip Society Liason), Biomaterials (Associate Editor), Journal of Arthroplasty, Journal of Biomedical Materials Research, and other journals, and is a manuscript reviewer for over 20 journals in the fields of orthopaedic surgery, arthritis, bioengineering and biomaterials. Dr. Goodman has published over 475 peer-reviewed manuscripts in medical and bioengineering journals. Dr. Goodman and co-workers have received awards for their research from the Society for Biomaterials, Orthopaedic Research Society, the American Orthopaedic Association, Western Orthopaedic Association, and the Association of Bone and Joint Surgeons. Dr. Goodman was awarded the Clemson Award for Basic Research from the Society For Biomaterials in May 2000. He was the President of the Society For Biomaterials (2001-2) and served on the Board of Directors of the Orthopaedic Research Society. Dr. Goodman served as Co-Chair for the 1995, 2000 and 2007 NIH/AAOS-sponsored workshops on Implant Wear. Dr. Goodman was recognized as a Fellow, Biomaterials Science and Engineering (FBSE) by the International Union of Societies, Biomaterials Science and Engineering in May 2004, a Fellow of the Japanese Society of the Promotion of Science in 2011, a Fellow of the American Institute of Medical and Biological Engineers in 2012 and a Fellow of the International Combined Orthopaedic Research Societies in 2016.
|Edward Greenfield, PhD
Dr. Greenfield is a Full Professor and the Director of Research in the Department of Orthopaedics at Case Western Reserve University. His PhD from the University of North Carolina-Chapel Hill focused on mechanisms of mineralization and he completed a post-doctoral fellowship on osteoclast biology at Washington University in St. Louis.
Dr. Greenfield is the director of an NIH training grant. He has served on a wide variety of NIH study sections and has also reviewed grant applications for numerous other funding agencies. He also reviews manuscripts for many journals and recently joined the editorial board of the Journal of Biological Chemistry.
Dr. Greenfield’s research focuses on cellular regulation of bone turnover in response to cytokines, hormones, orthopaedic wear debris, and bacteria. He has also recently begun a major research program on mechanisms of metastasis and tumorigenesis in osteosarcoma.
|Marian T. Hannan DSc, MPH
Dr. Hannan is an Associate Professor of Medicine at Harvard Medical School. She is also a Senior Scientist at the Institute for Aging Research at Hebrew SeniorLife in Boston and Co-Director of the Musculoskeletal Research Center. She received her undergraduate degree at the University of California, Berkeley, the Master of Public Health degree at Yale University School of Medicine and her doctorate in Epidemiology at Boston University School of Medicine. She is the Editor-in-Chief of the journal Arthritis Care & Research.
Dr. Hannan is currently conducting research on the epidemiology of age-related osteoporosis and arthritis; the influence of foot disorders on physical function and falls; and dietary and other risk factors that lead to bone loss. She has published in over 50 scientific journals, including the New England Journal of Medicine. In 2000, she received the prestigious Distinguished Scholar Award from the Association of Rheumatology Health Professionals.
Dr. Hannan is a well respected speaker at the research sessions of national meetings as well as at local schools of medicine. Dr. Hannan collaborates closely with other investigators in the large Musculoskeletal Research Center at the Institute for Aging Research, using the combined expertise of nutritional epidemiologists, geneticists, molecular biologists and statisticians to quantify risk factors contributing to bone loss and musculoskeletal diseases. She is the principal investigator on a number of National Institutes of Health grants, and has had continuous NIH funding since 1996.
At Harvard Medical School, Dr. Hannan teaches a first-year course on clinical epidemiology (for which she received the Excellence in Teaching Award in 2003) and lectures in the HMS geriatrics fellowship program. She also teaches a course on the epidemiology of aging at the Harvard School of Public Health. Since 2004, Dr. Hannan has served on several NIH study sections reviewing grant applications and was a member of the NIH Neurological, Aging, and Musculoskeletal Epidemiology Study Section.
|Howard J. Hillstrom, PhD
Dr. Hillstrom is Director, Leon Root, MD Motion Analysis Lab (LRMALab) at the Hospital for Special Surgery (HSS) in New York, New York. His philosophy for research in the neuro-musculoskeletal system is that structure and function are intimately related on multiple scales (i.e. from cellular to whole body). With 28 years of experience in directing motion analysis laboratories, conducting in vivo and in vitro research in upper and lower extremity clinically relevant biomechanically based problems and assisting with clinical gait analysis, he has observed that abnormal (e.g. malaligned) structures are associated with aberrant function (e.g. gait). When structures (e.g. alignment) are improved through conservative (e.g. orthoses) or surgical care, improved function generally results. The goals of his research are to improve our understanding of the pathomechanical mechanism(s) for OA onset and progression as well as quantify changes in function (e.g. gait), pain and quality of life following surgical or non-surgical realignment (e.g. genu varum) in individuals with OA.
As Director of the Leon Root, MD Motion Analysis Laboratory, he oversees the technical aspects of the motion analysis component of his research which includes insuring that system accuracies, calibrations, and data quality is within specification. Dr. Hillstrom collaborates with several national and international investigators examining subject-specific modeling of joint stress, conservative and surgical treatment efficacy, the effect of treatment upon disability and pain, and overall quality of life for those afflicted with osteoarthritis (OA). In particular he is interested in the link between biomechanics and pathophysiology in this disease towards the goal of informing physicians and patients novel ways in which to modify onset and progression of OA.
|Joshua J. Jacobs, MD
Dr. Jacobs, received a Bachelor of Science degree in Materials Science and Engineering from Northwestern University and graduated from the University of Illinois Medical School. In 1987, Dr. Jacobs completed his orthopaedic training at the Combined Harvard Orthopaedic Residency Program in Boston. Dr. Jacobs then completed a one-year fellowship in Adult Reconstructive Orthopaedic Surgery at Rush University Medical Center under the direction of Dr. Jorge Galante.
Dr. Jacobs has remained at Rush since his fellowship training and currently is the William A. Hark, M.D./Susanne G. Swift Professor and Chairman of the Department of Orthopaedic Surgery. At Rush University Dr. Jacobs also serves as the Associate Provost for Research. In addition, Dr. Jacobs is an Adjunct Professor of Materials Science and Engineering at Northwestern University. His major research focus is on the biocompatibility of permanent orthopaedic implants, particularly joint replacement devices. Dr. Jacobs has published numerous peer-reviewed manuscripts, most of which focus on the biological consequences of material degradation from joint replacement implants. Dr. Jacobs has received several research awards including a Career Development Award from the Orthopedic Research and Education Foundation, the Otto Aufranc Award from The Hip Society. the Ann Doner Vaughan Kappa Delta Award, American Academy of Orthopaedic Surgeons/Orthopaedic Research Society, the Mark Coventry Award from the Knee Society and the 2011 Ken Ludema Best Paper Award from the International Conference on Wear of Materials.
Dr. Jacobs has served on the Special Grants Review Committee of National Institute of Arthritis, Musculoskeletal and Skin Diseases (NIAMS) and in 2005, he was appointed to the NIAMS Advisory Council for a four-year term. In 2000, he was named Fellow, American Institute for Medical and Biological Engineering and elected to the International Hip Society. Dr. Jacobs is the Past Chairman of the Council on Research, Quality Assessment and Technology of the American Academy of Orthopaedic Surgeons and Past President of the American Academy of Orthopaedic Surgeons, the Orthopaedic Research Society and the United States Bone and Joint Decade. Dr. Jacobs currently serves as a Director of the American Board of Orthopaedic Surgery.
|Susan B. Jaglal, PhD
Dr. Jaglal is the Vice-Chair Research and Professor in the Department of Physical Therapy at the University of Toronto. She holds the Toronto Rehabilitation Institute Chair at the University of Toronto where she is Associate Director of Research. She is also the Lead for training and mentorship in the AGEWELL Network of Centres of Excellence.
In 2015 she was inducted into the Canadian Academy of Health Sciences. She has published over 200 peer-reviewed journal articles. Her research areas include osteoporosis, spinal cord injury and rehabilitation health services with emphasis on utilization, appropriateness, self-management and knowledge translation. She holds a PhD in Epidemiology from the University of Toronto.
|Wendy Katzman, PT, DPTSc (DSc), OCS
Dr. Katzman is a Physical Therapist and Professor in the University of California Scan Francisco (UCSF) Department of Physical Therapy and Rehabilitation Science. She is a Board Certified Orthopedic Clinical Specialist. She received a Bachelor of Science degree in Physical Therapy from the University of Texas Medical Branch, Galveston, and a post-professional Doctorate of Rehabilitation Science from UCSF in collaboration with San Francisco State University. Dr. Katzman completed the UCSF Advanced Training in Clinical Research certificate program, and received a K12 Career Development award to study age-related kyphosis in women. Her research has expanded to include the development of preventative and rehabilitative strategies for improving kyphosis and musculoskeletal aging in both sexes, and she is funded by the National Institutes of Health, including the National Institute of Aging, Office of Research in Women's Health, and the National Institute of Arthritis and Musculoskeletal and Skin Diseases. In addition to her research, Dr. Katzman teaches community-based exercise classes in the Department of Physical Therapy and Rehabilitation Science Health and Wellness Center.
|Nancy Lane, MD (Chair)
Dr. Lane, Past-President, United States Bone and Joint Decade (USBJD), and Chair, USBJD Young Investigators Initiative, is director of the Center for Healthy Aging, and co-director of the NIH funded BIRCWH program, and Professor of Medicine and Rheumatology at the University of California at Davis Medical Center. Dr. Lane earned her medical degree at the University of California at San Francisco and completed a fellowship in rheumatology at Palo Alto Veterans Administration Hospital in Palo Alto, California, and Stanford University Medical Center in Stanford, California. Dr. Lane is a co-editor for Arthritis and Rheumatism.
Dr. Lane is currently co-editor of Arthritis and Rheumatism. She is also on the editorial board of the Journal of Bone and Mineral Research, Osteoporosis International, and Arthritis Research, She is also a consultant reviewer for numerous peer-reviewed journals, among them JAMA, Journal of Bone and Mineral Research, Annals of Internal Medicine, and Journal of Bone and Joint Surgery. Dr. Lane is a frequent lecturer on osteoporosis and the author of hundreds of journal articles, book chapters, books, and abstracts and is fully funded NIH researcher on the epidemiology and genetics of hip OA in elderly women and men, osteoporosis and bone health. One special area of expertise is the use of PTH for the treatment of glucocorticoid-induced osteoporosis and the genetics epidemiology of hip OA in elderly women and men.
|Kristine Lohr, MD (USBJI Board Liaison)
Dr. Lohr received her MD from The University of Rochester School of Medicine and Dentistry, and completed her Internal Medicine Residency at Ohio State University Hospitals followed by a three-year research fellowship in Rheumatology at Duke University Medical Center. She served on the faculty at The Medical College of Wisconsin and University of Tennessee Health Sciences in Memphis before joining the University of Kentucky College of Medicine in 2007. Currently she is Chief of the Division of Rheumatology, Professor of Medicine, and Director of the Rheumatology Training Program at the University of Kentucky.
Dr. Lohr is a past recipient of the American College of Rheumatology (ACR) Research and Education Foundation Clinical Scholar Educator, and has served on several ACR committees, including the Annual Review Course, Annual Meeting Program Committee, and Committee on Workforce and Training. She represents the ACR on the USBJI Board, and is a committee member of its Young Investigator Program. She completed a six-year term on the American Board of Internal Medicine Rheumatology Subspecialty Board (testwriting). In 2014 she started a three-year term on the American Board of Internal Medicine Rheumatology Board. Her research interests focus on medical education and medical decision making.
|Anne-Marie Malfait, MD, PhD
Dr. Malfait is a Professor of Internal Medicine and the George W. Stuppy, MD, Chair of Arthritis at Rush University in Chicago IL. She received her MD degree in 1989 and her PhD in 1994, both from Ghent University in Belgium. Her early training was in rheumatology, followed by basic research training focused on cartilage metabolism in osteoarthritis. Her postdoctoral training at the Kennedy Institute of Rheumatology in London focused on the role of cytokines in inflammatory arthritis. In 2001, she joined the pharmaceutical industry, as part of a team for the development of disease-modifying osteoarthritis drugs (DMOADs). In 2009, she was recruited to Rush University, and established a research group studying pain in osteoarthritis using animal models. Her group studies the relationship between joint damage and the neurobiological processes that underlie OA pain, with the long-term goal to develop more efficacious and safer analgesics and DMOADs. Dr. Malfait has been an Associate Editor for Osteoarthritis and Cartilage and for Arthritis and Rheumatology since 2013. She currently serves on the Board of Directors of the Osteoarthritis Research Society International and is the incoming chair of the Committee on Research of the American College of Rheumatology. She feels passionate about osteoarthritis and pain research, and is strongly committed to motivating young investigators to join the efforts to study this very common disease that is rapidly becoming one of the major unmet medical needs in the world.
|Braxton D. Mitchell Jr., MPH, PhD
Dr. Mitchell is a genetic epidemiologist who has studied the genetics of complex diseases for many years. He has directed and played leading roles in numerous studies of cardiometabolic and bone health, whose goals have been to uncover the genetic architecture of these traits, identify genetic variants affecting disease risk, and to determine how the effects of these variants are modified by lifestyle risk factors. His research has been continuously funded by the NIH for over 25 years. His current research focuses on type 2 diabetes mellitus, cardiovascular disease, ischemic stroke, osteoporosis, osteoarthritis, and obesity. Dr. Mitchell has been a core investigator in the Amish Complex Disease Genetics program for the past 15 years, where he has led or participated in numerous discoveries of rare large effect variants that are enriched in this founder population. Current efforts in this study involve integration of whole genome and exome sequencing and other –omics data. He has published over 380 papers from his research.
Dr. Mitchell has served in multiple leadership positions in large consortia and on multiple editorial boards. He serves as the Associate Director of both the Mid-Atlantic Nutrition Obesity Research Center (NORC) and the Baltimore Diabetes Research Center (DRC). For these centers he directs a genomics core whose role is to provide support to investigators in their diabetes, obesity, and nutrition-related research. He has played an active role in the graduate program throughout his tenure at Maryland, including directing the Human Genetics Program for eight years. Throughout his career, he has mentored a large number of talented students, fellows, and junior faculty to pursue academic careers in translational research.
|Fackson Mwale, PhD
Dr. Mwale is a tenured Professor in the Department of Surgery at McGill University and a senior investigator at the Lady Davis Institute of the Sir B. Mortimer Davis Jewish General Hospital. He is an accomplished basic scientist with an international reputation for his innovative research. He is past President of the Canadian Orthopaedic Research Society (CORS). He is co-founder of Trepso Therapeutics, a novel technology developed to repair diseased intervertebral discs and founder of Intervertech. He has made contributions to the fields of extracellular matrix biology, osteoarthritis, spine biology and tissue engineering. His innovative contributions to these areas have earned him international recognition and acclaim.
Dr. Mwale received his PhD from the University of South Carolina, followed by a post-doctoral fellowship at McGill University with Dr. Robin Poole. Over the past 20 years, he has made fundamental contributions to research into the roles of the extracellular matrix in the growth plate, cartilage, bone and spine cell and molecular biology.
His research has furthered our understanding of diseases from growth plate anomalies, osteoarthritis and back pain. His studies have uncovered fundamental roles of Link N as a therapeutic agent for intervertebral discs and cartilage repair as well as the calcium sensing receptor in the pathogenesis of osteoarthritis and intervertebral discs.
Dr. Mwale has published over 100 peer-reviewed papers. He is a member of and has held leadership positions in several professional organizations, including the Spine Research Community (as one of the founders), and serves or has served on the editorial boards of several major journals, including JOR Spine, The International Journal of Biomaterials, World Journal of Orthopaedics, The Open Orthopaedics Journal, The Open Biomedical Engineering Journal and The Journal of Clinical Rehabilitative Tissue Engineering Research. He currently serves as a grant reviewer at the CIHR and NIH study sections. He served as a member of the Skeletal Biology Structure and Regeneration [SBSR] study section from 2013 to 2017. He was recently invited to serve again but this time as a member of the Musculoskeletal Tissue Engineering Study Section, Center for Scientific Review, for the term beginning July 01, 2018 and ending June 30, 2024.
He was one of the invited scientists to NIAMS in Washington to a round table with other experts in the field to discuss the future of spine research. Dr. Mwale was recognized with the honorary status of Fellow of International Orthopaedic Research (FIOR) of the ICORS International College of Fellows. His other honors include the ORS young investigator award, the Berton Rahn Prize Award, the Hansjörg Wyss Award, the North American Spine Society Award, the Founders medal and the North American Spine Society (NASS) Award, which was featured in the NASS daily news. Dr. Mwale co-chaired the Canadian Connective Tissue Society twice in 2005 and 2011 and became the president. He started the Research Interest Group at the Orthopedics Research Society in 2011 in Long Beach, California and founded the Spine Research Community, a group comprising of more than 800 clinicians, basic scientists and fellows. In 2010, he co-organized the Stem and Regenerative Workshop in Ottawa and the Spine Workshop in Kyoto, Japan. Dr Mwale recently developed PrimeGrowthTMMedia system for the long-term culture of whole discs with vertebrae, PrimeGrowthTMdisc cell media and PrimeStemTMan optimized stem cell culture media sold by Wisent Bioproducts. He is the current program chair of the Canadian Orthopedic Research Society and Co-organizer of the 2019 Combined Meeting of Orthopaedic Research Societies in Montreal, Canada
|Brian Noehren PT, PhD
Dr. Noehren is an associate professor in Physical Therapy and Orthopaedic Surgery at the University of Kentucky. He received is masters in physical therapy from the University of Connecticut in 2001 and his Ph.D in Biomechanics and Movement Science from the University of Delaware in 2009. He has been on faculty at the University of Kentucky since 2009. Brian is a clinician scientist with a focused research program dedicated to understanding how muscle function and biomechanics is affected in common orthopedic conditions (anterior cruciate ligament tears, osteoarthritis, total knee replacements). The long term goal of this work is to develop new treatments to improve patient outcomes. His work spans defining the cellular adaptations within muscle, to whole muscle imaging, up to using inverse kinematics and kinetics to observe the impact on movement mechanics. He also continues to practice physical therapy and directs the runners clinic at the University of Kentucky. Brian is a fellow of the American College of Sports Medicine and has also received numerous awards for his work including the Eugene Michels Young Investigator award from the American Physical Therapy Association. He is funded by the National Institutes of Health and has also been funded through the National Science Foundation, and several foundations.
|Jacques E. Nör, DDS, MS, PhD
Dr. Nör is Professor of Dentistry (Department of Cariology, Restorative Sciences and Endodontics), Professor of Otolaryngology (Medical School) and Professor of Biomedical Engineering (College of Engineering) at the University of Michigan. He has served as a member of the National Institutes of Health (NIH) study sections and is the principal investigator for NIH grants.
Dr. Nör is Associate Editor of the Journal of Dental Research and serves on several other Editorial Boards. His broad research interests are in angiogenesis and in stem cell biology. His current research foci are the study of mechanisms regulating the vascularization of head and neck tumors, and the study of dental pulp stem cell differentiation in the context of dental tissue engineering.
|Regis H. O'Keefe, MD, PhD
Dr. O’Keefe is the Fred C. Reynolds Professor and Chair, Department of Orthopaedic Surgery at Washington University School of Medicine in St. Louis, Missouri. Dr. O’Keefe earned his BA in philosophy and religious studies and graduated magna cum laude at Yale University in New Haven, Connecticut. After earning his medical degree from Harvard Medical School in Boston, Massachusetts, he completed a Ph.D. in biochemistry and biophysics from the University of Rochester School of Medicine and Dentistry. Dr. O’Keefe served his internship in surgery at New England Deaconess Hospital in Boston, his residency in orthopaedics at the University of Rochester Medical Center and completed an oncology fellowship at the Massachusetts General Hospital. In 1993, he joined the faculty at the University of Rochester. Dr. O’Keefe previously served as the Marjorie Strong Wehle Professor and Chair, Department of Orthopaedics and Rehabilitation and Associate Dean of Clinical Affairs at the University of Rochester School of Medicine and Dentistry.
Dr. O’Keefe has authored or coauthored over 290 articles, more than 300 abstracts, 16 book chapters and reviews concerning bone repair and development, cancer, inflammatory diseases of bone, genetics, and related topics. Most of his research has been supported by NIH grants, and his NIH funding has consistently placed him among the most highly funded orthopaedic surgeon-clinician scientists in the United States. In 2012 Dr. O’Keefe received a 5 year program Center of Research Translation program grant from the NIH. This award provides $7.5 million dollars to study factors regulating stem cell populations during bone and cartilage repair.
He has served as an associate editor of the Journal of Bone and Mineral Research and he is currently an associate editor of Bone. Dr. O’Keefe has served in numerous leadership roles in national orthopaedic organizations. Dr. O’Keefe is a member of the Board of Directors of the American Board of Orthopaedic Surgery (ABOS). In addition, he is the President of the American Orthopaedic Association (AOA). He served for more 7 years as a member of the Orthopaedic Research and Education Foundation, including service in the role of Secretary of that organization. Dr. O’Keefe is a past-President of the Orthopaedic Research Society (ORS). He also served the ORS as Treasurer and as a member of the Program Committee. He is the past-President of the United States Bone and Joint Decade, an international coalition of healthcare organizations aimed at decreasing the incidence of bone and joint disorders. Dr. O’Keefe is also the past-Chair of the Skeletal Biology and Skeletal Regeneration Study Section for the National Institutes of Health’s Center for Scientific Review and he has served on the Advisory Council of the National Institutes of Health (NIH) National Arthritis and Musculoskeletal and Skin Diseases (NIAMS) as well as the National Institutes of Health Council of Councils (COC) Advisory Council that reviews trans-NIH initiatives. Dr. O’Keefe has served as the Chair of the American Academy of Orthopaedic American Academy of Orthopaedic Surgeons’ Clinician Scientist Committee. He also has directed the Orthopaedic Research and Education Foundation’s Grant Writing Workshop, a program that mentors young scientists in the critical skill of grant writing. He is a member of the American Association of Physicians (AAP).
Dr. O’Keefe has received a variety of teaching and scientific awards including the prestigious ABC Traveling Fellowship from the American Orthopaedic Association and the Kappa Delta Award, recognizing excellence in orthopaedic research. Dr. O’Keefe has worked diligently in his career to promote and advance the basic understanding of musculoskeletal diseases and to translate these discoveries into therapies designed to improve the care of orthopaedic patients.
|J. Edward Puzas, PhD
Dr. Puzas is the Donald and Mary Clark Professor of Orthopaedics at the University of Rochester School of Medicine and Dentistry, Rochester, New York. He has been involved in basic and clinical research related to musculoskeletal diseases for the past 30 years.
Dr. Puzas’ major areas of interest are the functioning of bone cells in diseases such as osteoporosis, environmental toxin exposure and its role in skeletal metabolism and the mechanism of the genesis of osteoarthritis. His programs have been continuously funded by the NIH and other foundations.
Dr. Puzas is a Past President of the Orthopaedic Research Society (ORS) and the Past President of the United States Bone and Joint Initiative (USBJI) (formerly known as United States Bone and Joint Decade). He was the Sr. Associate Dean for Basic Research at the University of Rochester from 2009-2015. He is a founding member of the faculty for the USBJI Young Investigators Initiative.
|Stephen N. Robinovitch, PhD
Dr. Robinovitch received his B.App.Sc. in mechanical engineering from the University of British Columbia in 1988, his M.Sc. in mechanical engineering from M.I.T. in 1990, and his Ph.D. in medical engineering from the Harvard/M.I.T. program in Health, Science, and Technology in 1995. Between 1995-2000, he was an Assistant Professor, In-Residence in the Department of Orthopaedic Surgery at the University of California, San Francisco, and Director of the Biomechanics Laboratory at San Francisco General Hospital.
In 2000, he joined the faculty of the School of Engineering Science and the School of Kinesiology at Simon Fraser University, Vancouver, Canada, where he was Assistant Professor between 2000-2003, and has been Associate Professor since 2003. He has been principal investigator on operating grants from the Whitaker Foundation, The Centers for Disease Control (RO1 award), the NIH (RO3 and RO1 awards), CIHR, and NSERC. In 2001, he received a New Investigator Award from CIHR, and in 2006, he was awarded a Canada Research Chair (Tier II) in Biomedical Engineering.
Dr. Robinovitch's research is focused on the development of improved techniques for preventing disability and injury, especially in elderly individuals. One goal of his research is to develop improved strategies for preventing fall-related hip fractures and wrist fractures in the elderly. Here, he is examining the role of energy- absorbing floors and hip padding devices in reducing impact forces and injury risk during falls. He is also investigating the cause of age-related changes in fall protective responses (e.g., use of the hands to brake the fall). Another goal of his research is to develop a better understanding of how neuromuscular and behavioral variables affect postural stability and mobility. For example, he is examining how strength, flexibility, and reaction time affect one's ability to recover balance by sway or stepping, with the aim of developing improved exercise programs for fall prevention.
|Ann Rosenthal, MD
Dr. Rosenthal received her MD from Johns Hopkins University School of Medicine and completed a residency in Internal Medicine at Strong Memorial Hospital of the University of Rochester. She received her rheumatology training at the Medical College of Wisconsin, where she developed her research interests in calcium crystal–associated arthritis. She received a post-doctoral fellowship from the Arthritis Foundation to begin her research career, and has been active in the field since that time, with national funding from both the Veteran’s Administration and the National Institutes of Health.
Dr. Rosenthal’s research interests currently concern the role of the extracellular matrix in calcium crystal formation in cartilage, pathologic mineralization in osteoarthritis, and musculoskeletal complication of diabetes. She is the author of over 80 original publications, numerous chapters and invited reviews, and has spoken at many national and international meetings. Dr. Rosenthal currently serves on a study section for NIH, and completed a 4 year term on the immunology/rheumatology study section for the Veteran’s Administration.
She is the Will and Cava Professor of Medicine and Chief of the Rheumatology Division at the Medical College of Wisconsin. She is also medical director of the VA translational research center, and vice chair for faculty development in the department of medicine.
She maintains an active clinical practice, has been elected a fellow in the American College of Physicians, and is the recipient of several teaching awards.
|Alice Ryan, PhD
A main focus of my research is the study of obesity, body fat distribution, intramuscular fat and their role in insulin resistance with emphasis on the effects of weight loss and exercise training on muscle and glucose metabolism in sedentary, overweight individuals. The basic research includes the study of mechanisms by which diet and exercise interventions (aerobic and resistive training) affect skeletal muscle and adipose tissue metabolism, insulin signaling and gene expression in muscle, and in vivo insulin action in sedentary older individuals.
In addition, my research involves the study of residual hemiparesis following stroke which leads to physical deconditioning and possibly muscle atrophy and abnormal metabolism due to disuse or aberrant neural innervation. We have described skeletal muscle atrophy and greater fat deposition within the muscle of the hemiparetic limb in chronic hemiparetic stroke patients which may contribute to functional disability and increased cardiovascular disease risk in chronic hemiparetic stroke patients. We are currently examining the muscle molecular phenotype and its relationship to gait deficit severity and interventions designed to prevent muscle atrophy and reduce insulin resistance which are needed to minimize the loss of functional independence and cardiovascular disease risk in older chronically disabled stroke patients.
|Stephen D. Waldman PhD, P.Eng.
Dr. Waldman is a Professor at Ryerson University and an Affiliated Scientist at the Keenan Research Centre of St. Michael's Hospital.
Dr. Waldman’s research program is centered on the engineering of functional orthopaedic tissues (articular cartilage, ligaments and the intervertebral disc) with specific focus on the effect of physical stimuli (mechanical and chemical factors). Currently, his research group is working on the development of tissue-specific bioreactors to accelerate tissue growth, the use of mechanical stimuli to impart functional mechanical properties and, investigating the regulation of specific mechanotransduction pathways.
He has received several awards for his research, most notably a Canada Research Chair (2003 and 2009), Early Researcher Award (2006), and a Queen’s University Chancellor’s Research Award (2007). Over the last ten years, he has personally and in collaboration with others, secured over $14 million in research funds from agencies such as: CIHR, NSERC, OCE, CFI, ORF, CAN and the US Army. He has also served as an invited member on several grant panel committees at CIHR (Musculoskeletal Health and Arthritis 2005, Regenerative Medicine 2005; Biomedical Engineering 2006-2010, Collaborative Health Research Projects 2014), Ontario Ministry of Economic Development and Innovation (2010-2012), and the Arthritis Society of Canada (2013).
|Cari Whyne, PhD
Dr. Whyne received a Bachelor of Science degree in Mechanical Engineering from Queen’s University and completed her doctorate in Bioengineering at the University of California, Berkeley and the University of California San Francisco.
Dr. Whyne is currently a Professor at the University of Toronto and is the Director of the Holland Bone and Joint Research Program at Sunnybrook Research Institute.
Dr. Whyne’s research interests focus on clinically translational bioengineering research, specifically in the areas of spinal metastases, lower extremity trauma and craniomaxillofacial reconstrction.
|Lidan You, PhD
Dr. You is a Associate Professor of Mechanical Engineering and Bioengineering, University of Toronto, Ontario, Canada
Dr. You is an Associate Professor at the University of Toronto with cross-appointments in the Department of Mechanical & Industrial Engineering (MIE) and the Institute of Biomaterials and Biomedical Engineering (IBBME). Dr. You received the Early Researcher Award from the Ontario Ministry of Research and Innovation in 2009, the Duggan Medal from Canadian Society of Mechanical Engineering in 2011, and is elected to a Fellow of Canadian Society of Mechanical Engineering in 2015. Dr. You is the director of Cellular Biomechanics Laboratory at the University of Toronto. Her research is focused on solving biomechanical questions in muscular skeletal system at the cellular level. In specific, her team is working on the anti-resorptive effect of mechanical loading on bone tissue; pressure effect on bone cell mechanotransduction; mechanical loading effect on bone metastasis; osteocyte mechanosensitivity in diabetic condition, and the advanced microfluidic system for bone cell mechanotransduction study.
|Albert J. M. Yee, MD, MSc, FRCSC
Dr. Yee is the Holland Musculoskeletal Program Chief and the Head of the Division of Orthopaedic Surgery at Sunnybrook Health Sciences Centre, where he holds the Marvin Tile Chair in Orthopaedic Surgery. Dr Yee is an Orthopaedic Spine Surgeon at Sunnybrook Health Sciences Centre, an Associate Scientist (Physical Sciences Platform) at Sunnybrook Research Institute and a Consultant in Surgical Oncology, Bone Metastasis Clinic, Odette Cancer Centre. He is a Full Professor at the University of Toronto (U of T), Department of Surgery and Full Member of the Institute of Medical Sciences (IMS) with a cross appointment in the Institute of Biomaterials and Biomedical Engineering (IBBME) at U of T. He is the Co-Director of the U of T Department of Surgery Spine Program and Vice-Chair Research, U of T Division of Orthopaedic Surgery.
As a surgeon-researcher, Dr. Yee has a clinical interest in adult degenerative, traumatic, and metastatic spinal disease. He is a translational researcher with interest in new therapies for the treatment of adult degenerative and vertebral metastatic disease. The ultimate goal of Dr. Yee's spine research program is to bring forth novel therapies from the bench-top to clinical setting. As such, the development and use of preclinical models in surgery are important in evaluating potential advances in therapies for the treating spinal disorders (e.g. vertebral metastatic photodynamic therapy and radiofrequency ablation). The fundamental aspects of understanding cell-matrix interactions in intervertebral disc biology and cancer metastasis will further the development and preclinical evaluation of minimally invasive surgery (MIS) local spine strategies targeted against degenerative and metastatic spine conditions.
|Yuqing Zhang, DSc
Dr. Zhang is a professor of Medicine in Residence at Massachusetts General Hospital, Harvard School of Medicine. He has devoted most of his efforts to conduct epidemiologic studies of risk factors for rheumatic diseases and musculoskeletal conditions. These studies have included the descriptive epidemiology of musculoskeletal conditions and rheumatic diseases, risk factors for the occurrence and sequelae of these diseases, and research methodologies in rheumatic and musculoskeletal conditions. He has developed and applied novel epidemiologic and statistical methods to address different research questions in rheumatic diseases, including correlated data analyses, the self-matched case-control study design, statistical methods in longitudinal studies of knee pain, group-based trajectory analyses, and internet-based case-crossover study design to identify triggers for disease flares.
|Christopher Jacobs, PhD
Dr. Jacobs was Associate Professor in the Biomedical Engineering Department of Columbia University. His research focused on understanding the molecular mechanisms that cells use to sense and respond to their mechanical environment, including investigation of the cell cytoskeleton, integrins, and the primary cilium. Dr. Jacobs introduced the technique used in the Young Investigator Initiative program to train participants on how to develop specific aims. Sadly Dr. Jacobs passed away on July 1, 2018.